NB 1-2

Segregation wave: variable, between S1 and S4.

The NB 1-2 clone consists of 16-24 interneurons, most of which project contralaterally. A single neuron (TB) is located apart from the clone and has a unique time of differentiation and projection pattern. The cell cluster forms three main fascicles. The first fascicle contacts the TB axon but continues to grow ipsilaterally (1-2Ii). The second fascicle projects through the posterior commissure of the neuromere (1-2Icp), and the third fascicle projects through the anterior commissure of the next neuromere (1-2Ica). 1 to 2 anterior neurons of the cluster are recognized by an anti invected (engrailed) antibody. These cells together with the interneurons of NB 7-3 (see below) form the posterior intermediate group of engrailed expressing cells (PIs; Cui and Doe, 1992). At stage 17 this cluster consists of about 6 cells located lateral to the ventromedial cluster of engrailed expressing neurons which is derived from midline progenitors (Patel et al., 1989a; Bossing and Technau, 1994) .

Flybrain    Development    Neuroblast Lineage    NB 1-2

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