Structural MB defects caused by overexpression of FAS II |
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Fig. 9. Structural MB defects caused by overexpression of FAS II.
Lateral views of larval MBs at wandering third instar stage. GAL4 drivers
are:
(A) elav-GAL4, (B-D) OK107, (E) 201Y and (F) 238Y. Reporters are UAS-mCD8::GFPin all cases (green). Insets show cross sections of peduncles with phalloidin staining (magenta). Arrowhead in A, malformed thin dorsal lobe.
(B) MB with type 1 defects (Table 2). Note the blunt medial lobe as compared with the wild-type medial lobe in F, which terminates in three blobs.
(C) MB with type 2 defects. Note the malformed thin dorsal lobe (arrowhead).
(D) MB with type 3 defects. Note the malformed medial lobe (arrowhead) and expansion of the dorsal lobe. Scale bar: 20 mm. DL, dorsal lobe; ML, medial lobe; Ped, peduncle.
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